Data has been obtained in a study of antigen recognition of blood-derived T cells. In this study, an IFNgamma ELISPOT was done with PBMC loaded with peptide pools, each consisting of 10 15-mers, which overlap with 11 aminoacids.

Transcriptomic data has been generated on PB-monocytes in healthy controls, RA and SLE....

Data has been generated by multiplex analysis on the response of human MoDC to yeast, spheroplasts, pseudohyphae and spores. Human blood contains myeloid (mDCs) and plasmacytoid (pDCs) dendritic cells that differ in cytokine secretion pattern and responsiveness to microbial stimuli. We found that LP...

...L activation, 70 evaluated patients). This analysis for the first time showed a clinical correlation of induced immune responses as measured in the blood with outcome, as there have been so far statistically significantly less events in stage III patients showing good CTL reponses (IFN-y Elispot) to...

...actions with and killed antigen-bearing DC, limiting the ability of these DCs to activate naive CD4+ and CD8+ T cells. The inducible recruitment of blood-borne effector and memory T cells to lymph nodes may represent a mechanism for terminating primary and limiting secondary immune responses. In add...

...une system as well as human specific infections in vivo. We established “human hemato-lymphoid-system mice” by transplanting human CD34+ cord blood cells into irradiated newborn Rag2-/-gc-/- mice, leading to de novo development of human B, T, and dendritic cells; formation of structured primar...

...These different cell types have a different distribution in the blood as compared to other lymphoïd organs. We characterized these subtypes in the blood by single-cell multiparametric analysis. Our preliminary results indicate these subtypes in the blood correspond to homogeneous different populati...

...lanoma lesions following vaccination were found to have mounted a significant increase in the frequency of vaccine specific CTL in their peripheral blood and the appearance of a measurable CTL-frequency was seen between 8-13w after the first vaccine, furthermore, regression or stabilization of metas...