Study on the possibility of DC activation via inflammatory signals

We obtained data on the effect of pro-inflammatory stroma-derived cytokines on DC in vivo. Our investigation has shown that, in the absence of additional stimuli, such inflammatory signals are ineffectual in promoting DC activation and cannot substitute for engagement of innate receptors directly on DC.

• stimulus type
• cytokine

• tissue type
• stroma

• molecule type
• dectin-1,
• Biomaterial,
• CD4

• cell type
• T cell,
• dendritic cell

• experimental design type
• in vivo design experiment

created over 16 years ago (2 March 2009)    last modified over 13 years ago (28 September 2011)   [ RDF ]   [ RelFinder ]