Study on the possibility of DC activation via inflammatory signals
We obtained data on the effect of pro-inflammatory stroma-derived cytokines on DC in vivo. Our investigation has shown that, in the absence of additional stimuli, such inflammatory signals are ineffectual in promoting DC activation and cannot substitute for engagement of innate receptors directly on DC.
data set
preclinical study dataset
Dendritic cell quiescence during systemic inflammation driven by LPS stimulation of radioresistant cells in vivo.
cytokine
stroma
dectin-1
CD4
Biomaterial
dendritic cell
T cell
in vivo design experiment
Caetano Reis e Sousa
pro-inflammatory stroma-derived cytokines