Control of innate immunity by rapamycin ( mTOR)

We obtained data on the control of innate immunity by the mammalian target of Rapamycin (m-TOR) by enhancing TLR driven production of proinflammatory cytokines and type 1 interferons and by repressing posttranslational processing, via the inflammasome, of IL-1beta.

We will further analyse the impact of the m-TOR inhibitor Rapamycin on innate immunity.

• molecule type
• type I interferon,
• Toll like receptor,
• Interleukin-1 beta

• cell type
• cytokine

created over 14 years ago (9 December 2009)    last modified over 11 years ago (12 November 2012)   [ RDF ]   [ RelFinder ]