Control of innate immunity by rapamycin ( mTOR)
We obtained data on the control of innate immunity by the mammalian target of Rapamycin (m-TOR) by enhancing TLR driven production of proinflammatory cytokines and type 1 interferons and by repressing posttranslational processing, via the inflammasome, of IL-1beta.
We will further analyse the impact of the m-TOR inhibitor Rapamycin on innate immunity.
data set
proteomics dataset
Toll like receptor
cytokine
type I interferon
Interleukin-1 beta
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells.
Hermann Wagner