DC-Research Knowledge Portal: Phosphorothioate CpG DNA

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Anne O'Garra

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MRC - The National Institute for Medical Research

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Macrophages and myeloid DC, but not plasmacytoi...

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J.Immunol. 177, 7551 – 7558

Boonstra, A., Rajsbaum. R., Holman, M., Marques, R., Asselin-Paturel, C., Pereira, J.P., Bates, E.M., Akira, S., Vieira, P., Liu, Y-J., Trinchieri, G., and O’Garra,A

Bio Materials > molecular structure > Molecular entity > CpG > Phosphorothioate CpG DNA

Phosphorothioate CpG DNA

CpG

The CpG was used for stimulating DC. It was shown in mice that both IL-10 as well as IL-12 production is dependent on the signalling adaptor molecules either MyD88 or TRIF, respectively in response to CpG, LPS or PolyIC.

created over 16 years ago (4 March 2009) last modified over 13 years ago (28 September 2011) [ RDF ] [ RelFinder ]


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