Macrophage tolerance: CD47-SIRP-alpha-mediated signals matter

Takizawa H., Manz M.G.
Nat Immunol. 2007 Dec; 8(12):1287-9.

Inhibition of phagocyte activity depends on the ligation of SIRP- by CD47. New findings show that Sirpa polymorphisms influence the engraftment and tolerance of xenogeneic transplants in NOD-SCID mice.

URL: http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?PrId=3094&itool=AbstractPlus-def&uid=18026079&db=pubmed&url=http://dx.doi.org/10.1038/ni1207-1287

Pub Med: http://www.ncbi.nlm.nih.gov/pubmed/18026079

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