Role of STAT3 signalling in immunogenicity or tolerance

Data on the role of STAT3 signalling in directing DC-mediated responses toward immunogenicity or tolerance will be generated.

To this purpose, we will identify
(i) genes and
(ii) micro-RNA

selectively controlled by STAT3 in human MDDCs treated with proinflammatory or tolerogenic stimuli (including TLR ligands, cytokines and vitamin D3). This will shed light on the role of STAT3 signalling.

created over 14 years ago (24 February 2010)    last modified over 11 years ago (3 June 2013)   [ RDF ]   [ RelFinder ]