Mature DCs acquire the ability to efficiently present antigens associated with MHC molecules to T lymphocytes

We have obtained data on the ability of mMature DCs to efficiently present antigens associated with MHC molecules to T lymphocytes.

Dendritic cells (DCs) are major actors of innate and adaptive immune responses. Immature DCs express a great diversity of receptors at their cell surface, which provide them the ability to uptake antigen and induce an intracellular signal. DCs become mature after encountering soluble mediators or conserved pathogen associated molecular patterns (PAMPs) or after interacting with other cells. Mature DCs acquire the ability to efficiently present antigens associated with MHC molecules to T lymphocytes leading to the efficient priming of CD4+ and/or CD8+ T cells.

• cell type
• T cell,
• mature dendritic cell

• molecule type
• CD8,
• CD4

created over 16 years ago (2 March 2009)    last modified over 12 years ago (16 July 2012)   [ RDF ]   [ RelFinder ]