Comparison of induction of CTL responses in vivo

We have obtained data on the induction of CTL responses in vivo by immunization of in vitro matured DC versus CTL responses induced by sustained delivery of a maturation signal from a comparison in a murine model. PolyI:C12U (Ampligen) did not activate the murine bone-marrow derived DC. Similar experiments are being performed using a stabilised form of polyI:C.

• molecule type
• poly(I:C(12)U),
• Polyinosinic acid:polycytidylic acid

• cell type
• dendritic cell,
• cytotoxic T lymphocyte

• organism type
• Mus musculus

• experimental design type
• in vitro design experiment,
• in vivo design experiment

created over 15 years ago (2 March 2009)    last modified over 12 years ago (2 July 2012)   [ RDF ]   [ RelFinder ]