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Datasets  >  signalling dataset  >  Definition of the mode of a...

Definition of the mode of activation of RIG-I

signalling dataset

We have obtained data using electron microscopy to document the production and secretion of tubulovesicular structures by cells overexpressing VSV-G glycoprotein. These tubulovesicular structures contaminate recombinant viral preparations and play an important role in determining their innate activating potential. The protocols used in those studies have been published and expression vectors for GFP-RIG-I have been made available (outside of the DC-THERA Directory).

created over 8 years ago (2 March 2009)    last modified over 5 years ago (18 June 2012)   [ RDF Rdf ]   [ RelFinder Relfinder ]