Delivery of antigens in both murine and human DC into either the MHC I or MHC II presentation pathways

We obtained data on antigen delivery by a vector with ovalbumin and CMVpp65 in mice or human, respectively.

We used a MHC II presentation pathway targeting vector originally published by Wang et al. 1999. Proof of principle studies for antigen delivery have been performed with ovalbumin (murine studies) and CMVpp65 (human studies).

• molecule type
• Major histocompatibility complex class II,
• Ovalbumin,
• CMV pp65 peptide antigen,
• Major histocompatibility complex class I

• cell type
• dendritic cell

• organism type
• Mus musculus,
• Homo sapiens

• experimental design type
• in vivo design experiment

created over 16 years ago (2 March 2009)    last modified over 13 years ago (9 March 2012)   [ RDF ]   [ RelFinder ]