Delivery of antigens in both murine and human DC into either the MHC I or MHC II presentation pathwaysproteomics dataset
We obtained data on antigen delivery by a vector with ovalbumin and CMVpp65 in mice or human, respectively.
We used a MHC II presentation pathway targeting vector originally published by Wang et al. 1999. Proof of principle studies for antigen delivery have been performed with ovalbumin (murine studies) and CMVpp65 (human studies).
- molecule type
- CMV pp65 peptide antigen,
- Major histocompatibility complex class II,
- Major histocompatibility complex class I
- cell type
- dendritic cell
- experimental design type
- in vivo design experiment