Confocal for dynamics between DC and NK cells

The group has data available on a newly identified DC subset called IKDC producing IFNg and expressing TRAIL which can recognize and kill transformed tumor cells in vitro and in vivo. They performed a video-confocal microscopy overnight on cultures of tumor cells with IKDC. We visualized that IKDC generate long contacts and synapses with tumor cells and ultimately kill them within 4 hours.

• molecule type
• Interferon gamma,
• TNF-related apoptosis-inducing ligand

• cell type
• dendritic cell,
• natural killer cell,
• tumor cell

created over 15 years ago (2 March 2009)    last modified over 12 years ago (20 February 2012)   [ RDF ]   [ RelFinder ]