Normal donors

We set an in vitro system to study ex-vivo responses able to detect fona fide in vivo primed CD4+ T cells. We investigated spontaneous CD4+ T cell responses to these antigens in normal donors and in patients with high-grade cervical lesions, pancreas adenocarcinoma and advanced melanoma.

The antigens used were:
i) the E6 and E7 proteins of human papilloma viruses,
ii) the carcinoembryonic antigen (CEA) and
iii) the tumour specific antigen MAGE-A3.

created over 16 years ago (2 March 2009)    last modified over 13 years ago (28 September 2011)   [ RDF ]   [ RelFinder ]