Tri-Mix-mRNA DC vaccine

We have shown recently that the T cell stimulatory capacity of DCs pulsed with tumorantigen-derived peptides can be considerably increased by activating the DCs through electroporation with CD40L, CD70 and constitutively active TLR4 encoding mRNA (TriMix DCs).

This vaccine will also be tested in the multicentre trial.

• biomaterial type
• dendritic cell,
• Homo sapiens

created over 15 years ago (17 December 2009)    last modified over 13 years ago (28 September 2011)   [ RDF ]   [ RelFinder ]