Human monocyte derived dendritic cells

We used specific inhibitors to study the role of src-family tyrosine kinases in the maturation of human monocyte derived dendritic cells upon stimulation with several toll like receptor (TLR) agonists. The effect of these kinase inhibitors on the capacity of DC to be activated by a TLR2 (PAM3CSK4), TLR3 (Poly I:C), TLR5 (Flagellin), and TLR8 (Poly U) agonist was evaluated.

• organism type
• Homo sapiens

• cell type
• monocyte

• molecule type
• Toll like receptor

created over 15 years ago (2 April 2009)    last modified over 13 years ago (28 September 2011)   [ RDF ]   [ RelFinder ]