IFNalpha receptor -/- mice

These K/O mice were studied with regard to responses to viral infections. We used the mouse pox virus Ectromelia and MVA-BN. Coinfection with MVA-BN and Ectromilia protected the IFNalpha receptor -/- mice. The data show that MVA-BN can induce potent innate immune responses able to control viral replication to allow the specific immune response to eliminate Ectromelia in immune deficient mice.

created over 16 years ago (2 April 2009)    last modified over 13 years ago (28 September 2011)   [ RDF ]   [ RelFinder ]