has knowledgeable contact person
is biomaterial used in
Bio Materials  >  cell  >  T cell  >  gamma-delta t cell  >  Antigen-stimulated circulat...

Antigen-stimulated circulating gamma delta T lymphocytes

gamma-delta t cell

We investigated the interactions between human monocyte derived DCs (MDDC), generated in the presence of GM-CSF and IL-4 (IL-4 DC), and antigen-stimulated circulating gamma delta T lymphocytes, bearing the Vgamma2 TCR. The studies demonstrated for the first time the existence of a bidirectional activating interaction between DCs and gamma delta T lymphocytes activated by aminobiphosphonates. These data suggest a potential adjuvant role of this early cross-talk in the therapeutic activity of aminobiphosphonate drug that are currently used as anti-tumor drugs.

created over 8 years ago (1 April 2009)    last modified over 6 years ago (28 September 2011)   [ RDF Rdf ]   [ RelFinder Relfinder ]