Tumor-bearing mice

The immunotherapy potential of DC, pulsed with tumor antigens, was evaluated in EG7-OVA and P815 tumor models.

Depletion of natural regulatory T cells in these tumor bearing mice resulted in rejection of P815 cells, but not EG7-OVA, suggesting that regulatory T cells have a stronger impact on immune responses against weakly immunogenic or auto-antigen (P1A).

created over 15 years ago (4 March 2009)    last modified over 13 years ago (28 September 2011)   [ RDF ]   [ RelFinder ]