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MAGE-A3 peptide vaccine


Melanoma patients were vaccinated with 4 peptides (MAGE-A3, gp100, NA17 and tyrosinase) presented by HLA-A2 and monitored. We measured responses to these peptides injected with Montanide, not knowing whether the Montanide adjuvant was important for these T cell responses. We therefore injected the same peptides without adjuvant, and no response was observed. We conclude that Montanide had a clear adjuvant effect for the CD8 T cell responses measured against these four peptides.

created over 15 years ago (4 March 2009)    last modified over 12 years ago (28 September 2011)   [ RDF Rdf ]   [ RelFinder Relfinder ]