Real time and immunohistochemistry analysis

Real time and immunohistochemistry analysis was performed in a study to evaluate whether iNOS can serve as a prognostic factor in stage III melanoma survival. The analysis showed that both iNOS and COX-2 alone significantly predicted OS. The BRAF/NRAS mutation status did not significantly differ between patient groups, although iNOS significantly correlated with BRAF mutation frequency. Furthermore, iNOS and COX-2 were significantly linked to a number of metastatic lymph nodes. However, iNOS maintained its statistical significance together with a number of lymph nodes in the multivariate analysis and predicted OS, whereas COX-2 did.

created over 15 years ago (26 February 2010)    last modified over 13 years ago (28 September 2011)   [ RDF ]   [ RelFinder ]