Bilkent UniversityDC-THERA Third Party
The Department of Molecular Biology and Genetics Graduate Program leads to M.Sc. and Ph.D. degrees in Molecular Biology and Genetics. The department is equipped with modern facilities for gene analysis, cell biology, protein chemistry, recombinant DNA technology and animal experiments. The education is research oriented. Research laboratories of the department are used for graduate student training a The main research activities of the department are on molecular genetics, molecular biology, molecular cell biology, molecular virology, structure-function relationship of proteins and new biotechnologies. The research laboratories of the department are equipped with facilities and equipment needed for gene analysis, protein chemistry, recombinant DNA technology, cell biology, experimental animal research, monoclonal antibody production and biotechnology. Current research programs are in the fields molecular genetics, molecular biology, cell biology, protein structure-function relationships, molecular virology and new biotechnologies. Genes involved in genetic predisposition to cancer and tumor suppression (p53, SMAD2, SMAD4, BRCA1, BRCA2, MLH1, MSH2) are studied in the Turkish population. The Molecular virology program concentrates on the viral etiology of chronic liver diseases and hepatocellular carcinoma (Hepatitis B and C viruses). Biological functions of proteins involved in tumor suppression (p33, p53, p73, p16, p130, BRCA1), apoptosis (bcl-2, bax, bcl-x), cell cycle (cyclin-dependent kinase inhibitors, retinoblastoma family of proteins), DNA-damage response (p53, BRCA1, DNA-PK), cell-extracellular matrix interactions (syndecans) are studied. Regulation of gene transcription and cell signaling molecules are also studied. DNA- and antibody-based diagnostic tests for cancer and hepatitis viruses are developed. The department has established collaborative projects with national and international research institutions in Europe and The United States. TUBITAK-sponsored program allows selected Ph.D. students to perform long-term research training in foreign research institutions through collaborative research projects.