In vitro antigen presentation assay
comment: Data will be available from in-vitro pre-clinical tests on the pharmacodynamic activity of the fusion vaccines. This test will verify the capacity of the fusion vaccine to present certain tumour-antigen derived peptides corresponding to antigens present in the fused cancer cells. BruCells has met with the Dutch MEB for a Scientific Advice Meeting on January 10, 2008 in The Hague. The Dutch authorities consider that the proposed in-vitro pre-clinical tests are adequate to check the pharmacodynamic activity of the fusion vaccines and that no animal model tests would be necessary.
type: data set
type: preclinical study dataset
related to instance: In vitro priming of tumor-antigen specific T-cells
related to instance: In vitro recognition of fusion vaccine by T-cells
has knowledgeable: Robert Coffin