Montanide as adjuvant for vaccination with peptides
Melanoma patients were vaccinated with peptides (MAGE-A3, gp100, NA17 and tyrosinase), with and without montanide as adjuvant. No response was observed when vaccinating without the adjuvant. We conclude that Montanide had a clear adjuvant effect for the CD8 T cell responses measured against these four peptides.
Biomaterial
vaccine
Pierre Coulie
Thierry Boon
Standardized method for the immuno-monitoring of DC vaccination trials
Immuno-monitoring of CD8 T cell responses in melanoma patients vaccinated with peptides plus adjuvant, viral vectors, or peptide-pulsed DC